I was heading towards diabetes when I was at 337 lbs. Some estimates suggest that huge numbers of Americans will be diabetic in the future, as we get more obese and older; maybe even decreasing life expectancy in the US!
Today, in the Lancet (a British medical journal):
The worldwide incidence, prevalence, and economic effect of type 2 diabetes are substantial. Since the disease is usually asymptomatic in its earliest stages, many cases remain undiagnosed for long periods. Upon diagnosis, many individuals already have diabetes-related complications.In the US population, screening for type 2 diabetes is cost effective when started between the ages of 30 years and 45 years, with screening repeated every 3–5 years.